A simple vector system to improve performance and utilisation of recombinant antibodies

@article{Martin2006ASV,
  title={A simple vector system to improve performance and utilisation of recombinant antibodies},
  author={C. Derek Martin and Gertrudis Rojas and Joanne N Mitchell and Karen J Vincent and Jiahua Wu and John McCafferty and Darren J Schofield},
  journal={BMC Biotechnology},
  year={2006},
  volume={6},
  pages={46 - 46}
}
BACKGROUND Isolation of recombinant antibody fragments from antibody libraries is well established using technologies such as phage display. Phage display vectors are ideal for efficient display of antibody fragments on the surface of bacteriophage particles. However, they are often inefficient for expression of soluble antibody fragments, and sub-cloning of selected antibody populations into dedicated soluble antibody fragment expression vectors can enhance expression. RESULTS We have… CONTINUE READING
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