A simple toxicological analysis of anabolic steroid preparations from the black market

@article{Pellegrini2012AST,
  title={A simple toxicological analysis of anabolic steroid preparations from the black market},
  author={Manuela Pellegrini and Maria Concetta Rotolo and Rita Di Giovannadrea and Roberta Pacifici and Simona Pichini},
  journal={Annales De Toxicologie Analytique},
  year={2012},
  volume={24},
  pages={67-72}
}
Objectives: A simple and rapid gas chromatography (GC) method with mass spectrometry (MS) detection was developed for the identification and quantification of anabolic steroids in pharmaceutical preparations from the black market. Material and Methods: After a liquid-liquid extraction of pharmaceutical products at acidic, neutral and basic pH with chloroform-isopropanol (9:1, v/v), the different steroids were separated by fused silica capillary column and detected by electron impact (EI)-MS in… 

Tables from this paper

Analysis of seized stanozolol formulations in South Brazil by liquid chromatography coupled to quadrupole time-of-flight-mass spectrometry

Anabolic-androgenic steroids (AAS) are synthetic derivatives of testosterone which are used medically for several diseases. However, misuse is commonly observed by athletes to promote enhancement of

Reliable identification and quantification of anabolic androgenic steroids in dietary supplements by using gas chromatography coupled to triple quadrupole mass spectrometry.

The developed analytical method was successfully applied to the analysis of 67 commercially available dietary supplements and in 5 cases one or more steroid-type compounds were found in the concentration of 5 ng g-1 - 100 μg g- 1 , which might result adverse analytical findings in athletes.

Measurement of iodide and caffeine content in cellulite reduction cosmetic products sold in the European market

Two simple liquid chromatography (LC) separation methods coupled with ultraviolet diode array (UV-DAD) and an electrospray ionisation mass spectrometry (ESI-MS) detection have been developed for the

Non-allowed Pharmacologically Active Substances in Physical and Sexual Performance Enhancing Products

Eventual health hazards caused by the hidden presence of pharmacologically active substances in physical and sexual performance enhancing products are reported.

Determination of anabolic-androgenic steroid adulterants in counterfeit drugs by UHPLC-MS/MS.

Forensic analysis of anabolic steroids tablets composition using attenuated total reflection Fourier transform infrared microspectroscopy (µATR‐FTIR) mapping

This methodology is promising for the analysis of anabolic steroid tablets, and can be used in a complementary way with techniques already consolidated in forensic laboratory routine for a better classification of questioned samples between authentic and falsified ones.

References

SHOWING 1-10 OF 16 REFERENCES

Analysis of confiscated black market drugs using chromatographic and mass spectrometric approaches.

In the context of house searches in Germany, numerous drugs were confiscated and subjected to chemical analysis, including anabolic agents such as various anabolic-androgenic steroids (stanozolol,

Systematic toxicological analysis of Indian herbal ready-to-chew pouches by gas chromatography mass spectrometry

The mg amounts of the two alkaloids found in the pouches together with the reported consumption of several pouche a day may be consistent with health risks, and should be investigated to investigate the possible presence of licit and illicit psychoactive compounds.

Position of chromatographic techniques in screening for detection of drugs or poisons in clinical and forensic toxicology and/or doping control

  • H. Maurer
  • Chemistry
    Clinical chemistry and laboratory medicine
  • 2004
GC-MS may become the gold standard in clinical and forensic toxicology and doping control if the costs of the apparatus will be markedly reduced, the current disadvantages like irreproducibility of fragmentation, reduction of ionization by matrix, etc. will be overcome, and finally if one of the increasing number of quite different techniques will become the apparatus standard.

Black Market in Anabolic Steroids—Analysis of Illegally Distributed Products

Forty-two products encountered in the illegal distribution channels were analyzed by gas chromatography/mass spectrometry and counterfeits of parabolan and primobolan products were found, mainly the cheaper agents nandrolone or testosterone derivatives were identified.

Advances in the analysis of non-allowed pharmacologically active substances in cosmetic products.

Nutritional supplements cross-contaminated and faked with doping substances.

Since 2002 new 'designer' steroids such as prostanozol, methasterone, androstatrienedione etc have been offered on the nutritional supplement market and also cross-contamination with these steroids are expected.