A simple technique to characterize proximal and peripheral nitric oxide exchange using constant flow exhalations and an axial diffusion model.

@article{Condorelli2007AST,
  title={A simple technique to characterize proximal and peripheral nitric oxide exchange using constant flow exhalations and an axial diffusion model.},
  author={Peter Condorelli and Hye-Won Shin and Anna S Aledia and Philip E Silkoff and Steven George},
  journal={Journal of applied physiology},
  year={2007},
  volume={102 1},
  pages={417-25}
}
The most common technique employed to describe pulmonary gas exchange of nitric oxide (NO) combines multiple constant flow exhalations with a two-compartment model (2CM) that neglects 1) the trumpet shape (increasing surface area per unit volume) of the airway tree and 2) gas phase axial diffusion of NO. However, recent evidence suggests that these features of the lungs are important determinants of NO exchange. The goal of this study is to present an algorithm that characterizes NO exchange… CONTINUE READING
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