• Biology, Medicine
  • Published in
    Journal of molecular…
    2002

A simple sensitive program for detecting internal repeats in sets of multiply aligned homologous proteins.

@article{Zhai2002ASS,
  title={A simple sensitive program for detecting internal repeats in sets of multiply aligned homologous proteins.},
  author={Yufeng Zhai and Milton H. Saier},
  journal={Journal of molecular microbiology and biotechnology},
  year={2002},
  volume={4 4},
  pages={
          375-7
        }
}
We designed a simple but sensitive program, IntraCompare, for identifying internal repeats in families of homologous proteins. The protein sequences are aligned (Clustal X), the regions to be compared are selected, and all potential repeat sequences are compared with all others. The output provides comparison scores (GAP program) expressed in standard deviations. 

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