A simple regression method for mapping quantitative trait loci in line crosses using flanking markers

@article{Haley1992ASR,
  title={A simple regression method for mapping quantitative trait loci in line crosses using flanking markers},
  author={C. Haley and S. Knott},
  journal={Heredity},
  year={1992},
  volume={69},
  pages={315-324}
}
  • C. Haley, S. Knott
  • Published 1992
  • Biology, Medicine
  • Heredity
  • The use of flanking marker methods has proved to be a powerful tool for the mapping of quantitative trait loci (QTL) in the segregating generations derived from crosses between inbred lines. Methods to analyse these data, based on maximum-likelihood, have been developed and provide good estimates of QTL effects in some situations. Maximum-likelihood methods are, however, relatively complex and can be computationally slow. In this paper we develop methods for mapping QTL based on multiple… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    R/qtl: QTL Mapping in Experimental Crosses
    • 2,358
    • Open Access
    Precision mapping of quantitative trait loci.
    • 2,887
    • Open Access
    Empirical threshold values for quantitative trait mapping.
    • 4,709
    • Open Access
    Multiple interval mapping for quantitative trait loci.
    • 872
    • Open Access
    Interval mapping of multiple quantitative trait loci.
    • 856
    • Highly Influenced
    • Open Access
    Multiple trait analysis of genetic mapping for quantitative trait loci.
    • 757
    • Open Access
    Permutation tests for multiple loci affecting a quantitative character.
    • 1,043
    • Open Access
    A statistical framework for quantitative trait mapping.
    • 587
    • Open Access

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 18 REFERENCES
    Generalized Linear Models
    • 13,309
    • Open Access
    Aspects of maximum likelihood methods for the mapping of quantitative trait loci in line crosses
    • 114
    • Open Access
    Biometrical genetics
    • 934
    • Open Access
    Genstat 5 Reference Manual
    • 1,385
    • Open Access
    Use of DNA fingerprints for the detection of major genes for quantitative traits in domestic species.
    • 23
    Sequential tests for the detection of linkage.
    • 1,516
    • Highly Influential