• DOI:10.1038/hdy.1992.131
Corpus ID: 6632019

A simple regression method for mapping quantitative trait loci in line crosses using flanking markers

@article{Haley1992ASR,
  title={A simple regression method for mapping quantitative trait loci in line crosses using flanking markers},
  author={C. Haley and S. Knott},
  journal={Heredity},
  year={1992},
  volume={69},
  pages={315-324}
}

C. Haley, S. Knott

Published 1992

Biology, Medicine

Heredity

The use of flanking marker methods has proved to be a powerful tool for the mapping of quantitative trait loci (QTL) in the segregating generations derived from crosses between inbred lines. Methods to analyse these data, based on maximum-likelihood, have been developed and provide good estimates of QTL effects in some situations. Maximum-likelihood methods are, however, relatively complex and can be computationally slow. In this paper we develop methods for mapping QTL based on multiple… CONTINUE READING

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