A simple protein folding algorithm using a binary code and secondary structure constraints.

@article{Sun1995ASP,
  title={A simple protein folding algorithm using a binary code and secondary structure constraints.},
  author={Shao Cong Sun and Paul D. Thomas and Ken A. Dill},
  journal={Protein engineering},
  year={1995},
  volume={8 8},
  pages={
          769-78
        }
}
We describe an algorithm to predict tertiary structures of small proteins. In contrast to most current folding algorithms, it uses very few energy parameters. Given the secondary structural elements in the sequence--alpha-helices and beta-strands--the algorithm searches the remaining conformational space of a simplified real-space representation of chains to find a minimum energy of an exceedingly simple potential function. The potential is based only on a single type of favorable interaction… CONTINUE READING

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