A simple method to monitor and control methanol feeding of Pichia pastoris fermentations using mid-IR spectroscopy.

Abstract

Mid-infrared FTIR spectroscopy is an efficient tool for the monitoring of bioprocesses, since it is fast and able to detect many compounds simultaneously. However, complex and time-consuming calibration procedures are still required, and have inhibited the spreading of these instruments. A simple and quick method to calibrate a FTIR instrument was developed… (More)

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Cite this paper

@article{Schenk2007ASM, title={A simple method to monitor and control methanol feeding of Pichia pastoris fermentations using mid-IR spectroscopy.}, author={Jonas Schenk and Ian William Marison and Urs von Stockar}, journal={Journal of biotechnology}, year={2007}, volume={128 2}, pages={344-53} }