A simple method for the analysis by MS/MS of underivatized amino acids on dry blood spots from newborn screening


The analysis by electrospray-ionization tandem mass spectrometry of amino acids with butyl esterification and isotopically labeled internal standard is routine in newborn screening laboratories worldwide. In the present study, we established a direct analysis method of higher accuracy that uses a non-deuterated internal standard. The automatic sampler and… (More)
DOI: 10.1007/s00726-011-0910-6

7 Figures and Tables


  • Presentations referencing similar topics