A simple device to apply equibiaxial strain to cells cultured on flexible membranes.

@article{Rana2008ASD,
  title={A simple device to apply equibiaxial strain to cells cultured on flexible membranes.},
  author={Obaida R. Rana and Carsten Zobel and Esra Saygili and Klara Brixius and Felix Gramley and Thomas M. Schimpf and Karl Mischke and Dirk A Frechen and Christian Knackstedt and Robert H. G. Schwinger and Patrick Schauerte and Erol Saygili},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2008},
  volume={294 1},
  pages={H532-40}
}
The biomechanical environment to which cells are exposed is important to their normal growth, development, interaction, and function. Accordingly, there has been much interest in studying the role of biomechanical forces in cell biology and pathophysiology. This has led to the introduction and even commercialization of many experimental devices. Many of the early devices were limited by the heterogeneity of deformation of cells cultivated in different locations of the culture plate membranes… CONTINUE READING