A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins.

@article{Patel2008ASC,
  title={A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins.},
  author={Rahul P Patel and Christian K Narkowicz and Joseph P Hutchinson and Emily Frances Hilder and Glenn A. Jacobson},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2008},
  volume={46 1},
  pages={30-5}
}
A simple, selective and accurate capillary electrophoresis (CE) method has been developed for the rapid separation and identification of various low molecular weight heparins (LMWHs) and unfractionated heparin. Separation and operational parameters were investigated using dalteparin sodium as the test LMWH. The developed method used a 70 cm fused silica capillary (50 microm i.d.) with a detection window 8.5 cm from the distal end. Phosphate electrolyte (pH 3.5; 50 mM), an applied voltage of -30… CONTINUE READING

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