A simple assay for platelet-mediated hemostasis in flowing whole blood (PFA-100): reproducibility and effects of sex and age.

@article{Sestito1999ASA,
  title={A simple assay for platelet-mediated hemostasis in flowing whole blood (PFA-100): reproducibility and effects of sex and age.},
  author={Alfonso Sestito and Alessandro Sciahbasi and Raffaele Landolfi and Attilio Maseri and Gaetano Antonio Lanza and Felicita Andreotti},
  journal={Cardiologia},
  year={1999},
  volume={44 7},
  pages={661-5}
}
BACKGROUND A simple assay for platelet-mediated hemostasis in flowing blood (PFA-100) has become available. Whole blood is aspirated through the central opening of a membrane coated with platelet agonists; the time required for a platelet thrombus to occlude the opening is defined as closure time; the shorter the closure time the greater the platelet aggregability. There are limited data on the normal range of values for this test, and the effects of sex and age are not known. The aim of this… CONTINUE READING

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