A simple and sensitive 'in-house' method for determining genotypic drug resistance in HIV-1.

@article{Lindstrm2003ASA,
  title={A simple and sensitive 'in-house' method for determining genotypic drug resistance in HIV-1.},
  author={Anna Lindstr{\"o}m and Jan Albert},
  journal={Journal of virological methods},
  year={2003},
  volume={107 1},
  pages={45-51}
}
Antiretroviral combination therapy is a major advance in the treatment of HIV infection, but development of antiretroviral resistance is still an important cause of treatment failure. Therefore, resistance testing was recommended recently for follow-up of HIV-1 infected individuals. The aim of this study was to develop a new genotypic resistance assay because simple and affordable assays with sufficient sensitivity for different genetic subtypes and low copy number samples are still lacking… CONTINUE READING