A simple and efficient method to rescue very virulent infectious bursal disease virus using SPF chickens

Abstract

Reverse genetic systems for efficient generation of very virulent infectious bursal disease virus (vvIBDV) are currently limited. In this study, we have developed a simple and efficient way to rescue vvIBDV using SPF chickens. The genome of a vvIBDV strain, HLJ0504, flanked by hammerhead and hepatitis delta ribozyme sequences, was cloned downstream of the… (More)
DOI: 10.1007/s00705-012-1256-4

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@article{Yu2012ASA, title={A simple and efficient method to rescue very virulent infectious bursal disease virus using SPF chickens}, author={Fei Yu and Xiaole Qi and Li Gao and Yongqiang Wang and Yulong Gao and Li-ting Qin and Honglei Gao and Xiaomei Wang}, journal={Archives of Virology}, year={2012}, volume={157}, pages={969-973} }