A simple and convenient approach for evaluation of the parameters of ligand-receptor interaction. Receptor blocking index and its application.

Abstract

A new approach for determination of the parameters for ligand-receptor interaction, which is based on so-called dilution coordinates, was developed earlier. Equations that allow evaluation of not only the affinity of ligand-receptor interaction but also of the amount of free (or occupied by corresponding ligand) receptors were suggested. The most important… (More)
DOI: 10.1002/jmr.875

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