A simple, sensitive and accurate method for rat paw volume measurement and its expediency in preclinical animal studies

@article{Shejawal2014ASS,
  title={A simple, sensitive and accurate method for rat paw volume measurement and its expediency in preclinical animal studies},
  author={Naresh Shejawal and S. Menon and Sunita Shailajan},
  journal={Human & Experimental Toxicology},
  year={2014},
  volume={33},
  pages={123 - 129}
}
Several methods are used to evaluate the inflammatory changes. Measurement of edema is the most commonly used method for evaluating artificially induced inflammation in rat model. In this context, we present a method for the measurement of volume of rat paw, in which two glass columns containing fluid are connected by a glass tube. Paw is immersed in one column and the other column is placed on weighing balance. Upon immersion of paw, equal volume of fluid displaced applies a force F, which… CONTINUE READING

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