• DOI:10.1080/10635150390235520
Corpus ID: 13857323

A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.

@article{Guindon2003ASF,
  title={A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.},
  author={S. Guindon and O. Gascuel},
  journal={Systematic biology},
  year={2003},
  volume={52 5},
  pages={
          696-704
        }
}

S. Guindon, O. Gascuel

Published 2003

Mathematics, Medicine

Systematic biology

The increase in the number of large data sets and the complexity of current probabilistic sequence evolution models necessitates fast and reliable phylogeny reconstruction methods. We describe a new approach, based on the maximum- likelihood principle, which clearly satisfies these requirements. The core of this method is a simple hill-climbing algorithm that adjusts tree topology and branch lengths simultaneously. This algorithm starts from an initial tree built by a fast distance-based method… CONTINUE READING

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