A silencer-like cis element for the testis-specific phosphoglycerate-kinase-2-encoding gene.

@article{Mizuno1992ASC,
  title={A silencer-like cis element for the testis-specific phosphoglycerate-kinase-2-encoding gene.},
  author={Keiko Mizuno and Masahide Goto and Yukito Masamune and Yoshiaki Nakanishi},
  journal={Gene},
  year={1992},
  volume={119 2},
  pages={293-7}
}
Phosphoglycerate kinase (PGK), a glycolytic enzyme, possesses two isozymes: somatic-type PGK-1 and testis-specific PGK-2, encoded by distinct genes. Tissue-specific expression of the two PGK-encoding genes (Pgk) seems to be transcriptionally controlled, since tissue distribution of the mRNAs coincides well with that of the proteins. In the present study, we determined the cis-acting DNA elements that regulate the transcription of mouse Pgk-2. A transient expression assay of DNAs having various… CONTINUE READING