A short-type peptidoglycan recognition protein from the silkworm: expression, characterization and involvement in the prophenoloxidase activation pathway.

@article{Chen2014ASP,
  title={A short-type peptidoglycan recognition protein from the silkworm: expression, characterization and involvement in the prophenoloxidase activation pathway.},
  author={Kangkang Chen and Chen Liu and Yan He and Haobo Jiang and Zhiqiang Lu},
  journal={Developmental and comparative immunology},
  year={2014},
  volume={45 1},
  pages={1-9}
}
Recognition of invading microbes as non-self is the first step of immune responses. In insects, peptidoglycan recognition proteins (PGRPs) detect peptidoglycans (PGs) of bacterial cell wall, leading to the activation of defense responses. Twelve PGRPs have been identified in the silkworm, Bombyx mori, through bioinformatics analysis. However, their biochemical functions are mostly uncharacterized. In this study, we found PGRP-S5 transcript levels were up-regulated in fat body and midgut after… CONTINUE READING
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