A short stereoselective total synthesis of the fusarium toxin equisetin.

Abstract

A short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated… (More)

Topics

Cite this paper

@article{Burke2000ASS, title={A short stereoselective total synthesis of the fusarium toxin equisetin.}, author={Lisa T Burke and Darren J Dixon and Steven V Ley and F{\'e}lix Rodr{\'i}guez}, journal={Organic letters}, year={2000}, volume={2 23}, pages={3611-3} }