A short peptide GPIGS promotes proliferation of hair bulb keratinocytes and accelerates hair regrowth in mice.

@article{Tsuruda2005ASP,
  title={A short peptide GPIGS promotes proliferation of hair bulb keratinocytes and accelerates hair regrowth in mice.},
  author={Akinori Tsuruda and Yasuhiro Kawano and Takaaki Maekawa and Syuichi Oka},
  journal={Biological & pharmaceutical bulletin},
  year={2005},
  volume={28 3},
  pages={485-9}
}
The aim of this study was to discover a novel agent that promotes hair growth. We carried out a screening test in 298 types of conditioned medium (CM) from cultures of bacteria by using a hair bulb keratinocyte (HBK) growth assay. As a result, we found a HBK growth factor in the CM of Bacillus sp. M18. This HBK growth factor was purified by collecting biologically active fractions in three steps, including HP-20 batch processing, LH-20 chromatography and C18 reverse-phase high-pressure liquid… CONTINUE READING