A short echo proton magnetic resonance spectroscopy study of the left mesial-temporal lobe in first-onset schizophrenic patients

@article{Bartha1999ASE,
  title={A short echo proton magnetic resonance spectroscopy study of the left mesial-temporal lobe in first-onset schizophrenic patients},
  author={R. Bartha and Y. Al-Semaan and P. Williamson and D. Drost and R. Neufeld},
  journal={Biological Psychiatry},
  year={1999},
  volume={45},
  pages={1403-1411}
}
BACKGROUND Past 1H magnetic resonance spectroscopy (MRS) studies of the temporal lobe in schizophrenic patients have shown decreased levels of N-acetylaspartate (NAA) suggesting reduced neuronal density in this region. However, the measured volumes have been large and included contributions from mostly white matter. METHODS Short echo 1H MRS was used to measure levels of NAA and other metabolites (i.e., glutamate and glutamine) from a 6 cm3 volume in the left mesial-temporal lobe of 11 first… Expand
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