A sheep model for the study of focal epilepsy with concurrent intracranial EEG and functional MRI.

Abstract

PURPOSE We describe a sheep model of penicillin-induced seizure activity using electroencephalography (EEG) and functional MRI (fMRI). METHODS Ten adult sheep were used. Spikes and seizures were generated by instillation of 8,000-10,000 IU of penicillin into the right prefrontal cortex via a specially designed port. Bilateral intracranial EEG was acquired… (More)

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Cite this paper

@article{Opdam2002ASM, title={A sheep model for the study of focal epilepsy with concurrent intracranial EEG and functional MRI.}, author={Helen Ingrid Opdam and Paolo Federico and Graeme D. Jackson and Joanne Buchanan and David F. Abbott and Gavin C A Fabinyi and Ari Syngeniotis and Milosh Vosmansky and John S. Archer and R. Mark Wellard and Rinaldo Bellomo}, journal={Epilepsia}, year={2002}, volume={43 8}, pages={779-87} }