A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules

Abstract

The SIV-infected rhesus macaque (Macaca mulatta) is the most established model of AIDS disease systems, providing insight into pathogenesis and a model system for testing novel vaccines. The understanding of cellular immune responses based on the identification and study of Major Histocompatibility Complex (MHC) molecules, including their MHC:peptide… (More)
DOI: 10.1007/s00251-011-0598-5

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Cite this paper

@inproceedings{Sette2011ASM, title={A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules}, author={Alessandro Sette and John Sidney and Scott Southwood and Carrie Colleen Buchanan Moore and Jessica R Berry and Courtney Dow and Kate Siobhan Bradley and Ilka Hoof and Mark G. Lewis and William H. Hildebrand and Curtis McMurtrey and Nancy A. Wilson and David I. Watkins and Bianca Moth{\'e}}, booktitle={Immunogenetics}, year={2011} }