A serum metabonomic study on the difference between alcohol- and HBV-induced liver cirrhosis by ultraperformance liquid chromatography coupled to mass spectrometry plus quadrupole time-of-flight mass spectrometry.

Abstract

BACKGROUND Liver cirrhosis is the fatal consequence of chronic hepatitis, making early diagnosis of liver cirrhosis critical. Liver biopsy is still the standard diagnostic method for liver cirrhosis, although its use in a broad population with alcoholism or hepatitis B virus (HBV) infection remains difficult. In this study, we used a metabonomic approach to… (More)

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@article{Lian2011ASM, title={A serum metabonomic study on the difference between alcohol- and HBV-induced liver cirrhosis by ultraperformance liquid chromatography coupled to mass spectrometry plus quadrupole time-of-flight mass spectrometry.}, author={Jiang-shan Lian and Wei Liu and Shao-rui Hao and Yong-zheng Guo and Hai-Jun Huang and De-ying Chen and Qing Xie and Xiao-Ping Pan and Wei Xu and Wen-xia Yuan and Lanjuan Li and Jian-rong Huang}, journal={Chinese medical journal}, year={2011}, volume={124 9}, pages={1367-73} }