A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer.

@article{Voltz1999ASM,
  title={A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer.},
  author={Raymond Voltz and S. Humayun Gultekin and Myrna R Rosenfeld and Elke Gerstner and Juliet Eichen and Jerome B. Posner and Josep Dalmau},
  journal={The New England journal of medicine},
  year={1999},
  volume={340 23},
  pages={
          1788-95
        }
}
BACKGROUND In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a paraneoplastic disorder. Paraneoplastic limbic or brain-stem encephalitis occurs more frequently with testicular cancer than with most other cancers. We sought antineuronal antibodies that might be used in a diagnostic test for this syndrome. METHODS Immunohistochemical and immunoblotting techniques were used to detect serum and cerebrospinal fluid antibodies. Serologic screening of a… CONTINUE READING
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