A sequence polymorphism in miR-608 predicts recurrence after radiotherapy for nasopharyngeal carcinoma.

@article{Zheng2013ASP,
  title={A sequence polymorphism in miR-608 predicts recurrence after radiotherapy for nasopharyngeal carcinoma.},
  author={Jian Zheng and Jieqiong Deng and Mang Xiao and Lei Yang and Liyuan Zhang and Yonghe You and Min Hu and Na Li and Hongchun Wu and Wei Li and Jiachun Lu and Yifeng Zhou},
  journal={Cancer research},
  year={2013},
  volume={73 16},
  pages={5151-62}
}
Nasopharyngeal carcinoma is treated with radiotherapy and other modalities, but there is little information on individual genetic factors to help predict and improve patient outcomes. Single-nucleotide polymorphisms (SNP) in mature microRNA (miRNA) sequences have the potential to exert broad impact as miRNAs target many mRNAs. The aim of this study was to evaluate the effects of SNPs in mature miRNA sequences on clinical outcome in patients with nasopharyngeal carcinoma receiving radiotherapy… CONTINUE READING
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