A sensitivity study of the safety factor for conduction in the myocardium

  title={A sensitivity study of the safety factor for conduction in the myocardium},
  author={Leonel Romero and Beatriz Tr{\'e}nor and J. D. Ferrero and Javier Saiz},
  journal={Computers in Cardiology, 2005},
The safety factor (SF) is an indicator of the safeness of electrical conduction in the myocardium. In the present work, we have studied the sensitivity of the SF defined by Shaw and Rudy to the integration interval (II) using computer simulations, and then defined and evaluated a new and simplified method to calculate SF (SFm). Our results reveal that the sensitivity of the SF to the II is negligible outside the depolarization phase, delimited by the instant when membrane potential derivative… CONTINUE READING
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