A sensitive micellar liquid chromatographic method for the rectification of enantiomers of esmolol, and determination of absolute configuration and elution order

@article{Alwera2020ASM,
  title={A sensitive micellar liquid chromatographic method for the rectification of enantiomers of esmolol, and determination of absolute configuration and elution order},
  author={Vijay Alwera and Suman Sehlangia and Shiv Alwera},
  journal={Journal of Liquid Chromatography & Related Technologies},
  year={2020},
  volume={43},
  pages={742 - 749}
}
  • Vijay Alwera, Suman Sehlangia, Shiv Alwera
  • Published 2020
  • Chemistry
  • Journal of Liquid Chromatography & Related Technologies
    • Abstract A green chromatographic method is proposed for the enantioseparation of Esmolol (Amino alcohol) in which aqueous solution of the mixed surfactants is used as the alternative of organic solvents. In this work, the diastereomeric derivatives of racemic esmolol were prepared, under microwave heating conditions, using highly reactive activated chiral esters of the (S)-levofloxacin, (S)-ketoprofen, and (S)-ibuprofen. The prepared diastereomeric derivatives were separated using surfactant… CONTINUE READING
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    References

    SHOWING 1-10 OF 37 REFERENCES
    An efficient method for the determination of enantiomeric purity of racemic amino acids using micellar chromatography, a green approach.
    • 2
    In Situ Derivatization of (RS)-Mexiletine and Enantioseparation Using Micellar Liquid Chromatography: A Green Approach
    • 3
    Micellar liquid chromatography for enantioseparation of β-adrenolytics using (S)-ketoprofen-based reagents
    • 4
    RP-HPLC enantioseparation of β-adrenolytics using micellar mobile phase without organic solvents.
    • 4
    (RS)-Propranolol: enantioseparation by HPLC using newly synthesized (S)-levofloxacin-based reagent, absolute configuration of diastereomers and recovery of native enantiomers by detagging.
    • 15
    Liquid chromatographic enantioseparation of three beta-adrenolytics using new derivatizing reagents synthesized from (S)-ketoprofen and confirmation of configuration of diastereomers.
    • 9
    Micellar liquid chromatography for the determination of drug materials in pharmaceutical preparations and biological samples
    • 105
    Reversed-phase liquid chromatography with mixed micellar mobile phases of Brij-35 and sodium dodecyl sulphate: a method for the analysis of basic compounds
    • 25
    Enantioseparations of 11 Amino Alcohols Using Di-n-amyl l-Tartrate–Boric Acid Complex as Chiral Mobile Phase Additive by RP-HPLC
    • 9
    Determination of Critical Micelle Concentration Values Using Capillary Electrophoresis Instrumentation
    • 192