A sensitive micellar liquid chromatographic method for the rectification of enantiomers of esmolol, and determination of absolute configuration and elution order

@article{Alwera2020ASM,
  title={A sensitive micellar liquid chromatographic method for the rectification of enantiomers of esmolol, and determination of absolute configuration and elution order},
  author={Vijay Alwera and Suman Sehlangia and Shiv Alwera},
  journal={Journal of Liquid Chromatography & Related Technologies},
  year={2020},
  volume={43},
  pages={742 - 749}
}
  • Vijay Alwera, Suman Sehlangia, Shiv Alwera
  • Published 2020
  • Chemistry
  • Journal of Liquid Chromatography & Related Technologies
  • Abstract A green chromatographic method is proposed for the enantioseparation of Esmolol (Amino alcohol) in which aqueous solution of the mixed surfactants is used as the alternative of organic solvents. In this work, the diastereomeric derivatives of racemic esmolol were prepared, under microwave heating conditions, using highly reactive activated chiral esters of the (S)-levofloxacin, (S)-ketoprofen, and (S)-ibuprofen. The prepared diastereomeric derivatives were separated using surfactant… CONTINUE READING

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