A sensitive and rapid mass spectrometric method for the simultaneous measurement of eight steroid hormones and CALIPER pediatric reference intervals.

@article{Kyriakopoulou2013ASA,
  title={A sensitive and rapid mass spectrometric method for the simultaneous measurement of eight steroid hormones and CALIPER pediatric reference intervals.},
  author={Lianna G Kyriakopoulou and Mehrdad Yazdanpanah and David A Colantonio and Man Khun Chan and Caitlin H Daly and Khosrow Adeli},
  journal={Clinical biochemistry},
  year={2013},
  volume={46 7-8},
  pages={642-51}
}
OBJECTIVES To develop an accurate assay and establish the normal reference intervals for serum cortisol, corticosterone, 11-deoxycortisol, androstenedione, 21-hydroxyprogesterone, testosterone, 17-hydroxyprogesterone, and progesterone. These steroids are commonly used as biomarkers for the diagnosis and monitoring of endocrine diseases such as congenital adrenal hyperplasia. Appropriate age- and gender-stratified reference intervals are essential in accurate interpretation of steroid hormone… CONTINUE READING