A sensitive and rapid assay for homologous recombination in mosquito cells: impact of vector topology and implications for gene targeting


Recent progress in insect transgenesis has been dramatic but existing transposon-based approaches are constrained by position effects and potential instability. Gene targeting would bring a number of benefits, however progress requires a better understanding of the mechanisms involved. Much can be learned in vitro since extrachromosomal recombination occurs… (More)
DOI: 10.1186/1471-2156-2-21


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