A self-expanding bifurcated endovascular graft for abdominal aortic aneurysm repair. An initial study in a canine model.

  title={A self-expanding bifurcated endovascular graft for abdominal aortic aneurysm repair. An initial study in a canine model.},
  author={Gregory John Wilson and Petr Klement and Yasushi Pedro Kato and J. B. Martin and Isaac John Khan and Rysler Alcime and J. P. Dereume and David C. Macgregor and Leonard Pinchuk},
  journal={ASAIO journal},
  volume={42 5},
Approximately 50,000 abdominal aortic aneurysms (AAAs) are surgically repaired annually in the United States. Endovascular grafts (EVGs) combine a stent and a vascular graft offering great potential for reduced morbidity, mortality, and hospital stay because of minimally invasive endoluminal placement through catheters. Because most AAAs extend into one or both iliac arteries, a bifurcated EVG (bEVG) was developed, consisting of a proximal aortic trunk divided into two distinct lumens or… 
Development of a Symmetric Canine Abdominal Aortic Aneurysm Model With Clinical Relevance for Endovascular Graft Studies
This model is feasible and suitable for endovascular graft healing studies, and Factor VIII/von Willebrand factor staining showed complete reendothelialization of the endarterectomized wall, with a moderate degree of intimal hyperplasia.
Prevention of Spinal Cord Ischemia in an Ovine Model of Abdominal Aortic Aneurysm Treated with a Self-Expanding Stent-Graft
The use of an internal shunt during aneurysm creation and internal iliac-to-external iliAC transposition prior to bifurcated stent-graft deployment prevented spinal ischemia in an ovine AAA model.
Experimental assessment of proximal stent-graft (InterVascular) fixation in human cadaveric infrarenal aortas.
These results suggest that there is a theoretical advantage of oversizing an aortic prosthesis and that sufficient anchorage is achieved in an aneurysm neck of 10 mm to prevent migration when fully deployed.
Mid-term fixation stability of the EndoVascular Technologies endograft. EVT Investigators.
AIM OF THE STUDY to determine the positional stability of the EndoVascular Technologies (EVT) endograft after endovascular aneurysm repair during morphologic changes of the abdominal aorta during
Poor long-term stability of the Corvita abdominal stentgraft.
  • Y. Georg, N. Settembre, N. Chakfé
  • Medicine
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
  • 2014
Experimental techniques and models in the study of the development and treatment of abdominal aortic aneurysm
A variety of animal models and experimental techniques have been described in the investigation of the pathophysiology of AAA and in the development of improved endovascular surgical and pharmacological therapies and some of the problems encountered in extrapolating experimental findings to the human condition are discussed.
Endovascular Aneurysm Repair: Magnetic Resonance Monitoring of Histological Organization Processes in the Excluded Aneurysm
The histopathologic organization of excluded aneurysms can be monitored by MRI and Progressive organization is indicated by decreasing SIs in T2- and an increasing signal increase in T1-weighted images after gadolinium bolus.
MRI Virtual Biopsies: Analysis of an Explanted Endovascular Device and Perspectives for the Future
The MRI analysis of the explanted AneuRx device illustrates the possibilities of this technique to characterize the interaction of the endovascular graft with the surrounding tissues and shows the greatest diffusion coefficient and the greatest anisotropy.
Early Experience with the Corvita Endoluminal Graft for Treatment of Arterial Injuries
The results showed that the Corvita low-profile endoluminal graft can be successfully used to treat arterial injuries but that it sometimes requires the placement of additional stents in patients with tortuous or tapering vessels.