A selective role for neuronal activity regulated pentraxin in the processing of sensory-specific incentive value.

@article{Johnson2007ASR,
  title={A selective role for neuronal activity regulated pentraxin in the processing of sensory-specific incentive value.},
  author={Alexander W. Johnson and Hans S. Crombag and Kogo Takamiya and Jay M Baraban and Peter C. Holland and Richard L. Huganir and Irving Michael Reti},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2007},
  volume={27 49},
  pages={13430-5}
}
Neuronal activity regulated pentraxin (Narp) is a secreted neuronal product which clusters AMPA receptors and regulates excitatory synaptogenesis. Although Narp is selectively enriched in brain, its role in behavior is not known. As Narp is expressed prominently in limbic regions, we examined whether Narp deletion affects performance on tasks used to assess motivational consequences of food-rewarded learning. Narp knock-out (KO) mice were unimpaired in learning simple pavlovian discriminations… CONTINUE READING