A selective fluorescent sensor for detecting lead in living cells.

  title={A selective fluorescent sensor for detecting lead in living cells.},
  author={Qiwen He and Evan W Miller and Audrey P Wong and Christopher J Chang},
  journal={Journal of the American Chemical Society},
  volume={128 29},
We present the synthesis, properties, and biological applications of Leadfluor-1 (LF1), a new water-soluble, turn-on fluorescent sensor that is capable of selectively imaging Pb2+ in aqueous solution and in living cells. LF1 combines a fluorescein chromophore and a pseudocrown receptor to provide good selectivity for Pb2+ over a range of biologically and environmentally relevant metal ions in aqueous solution, with sensitivity to parts per billion EPA limits for allowable lead in drinking water… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…