A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols.

@article{Machado2012ASP,
  title={A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols.},
  author={Hidevaldo B. Machado and Yasumasa Dekishima and Hao Luo and Ethan I Lan and James C. Liao},
  journal={Metabolic engineering},
  year={2012},
  volume={14 5},
  pages={504-11}
}
Production of green chemicals and fuels using metabolically engineered organisms has been a promising alternative to petroleum-based production. Higher chain alcohols (C4-C8) are of interest because they can be used as chemical feedstock as well as fuels. Recently, the feasibility of n-hexanol synthesis using Escherichia coli has been demonstrated by extending the modified Clostridium CoA-dependent n-butanol synthesis pathway, thereby elongating carbon chain length via reactions in reversed… CONTINUE READING

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