A segmentation/clustering model for the analysis of array CGH data.

  title={A segmentation/clustering model for the analysis of array CGH data.},
  author={Franck Picard and St{\'e}phane Robin and Emilie Lebarbier and J-J Daudin},
  volume={63 3},
Microarray-CGH (comparative genomic hybridization) experiments are used to detect and map chromosomal imbalances. A CGH profile can be viewed as a succession of segments that represent homogeneous regions in the genome whose representative sequences share the same relative copy number on average. Segmentation methods constitute a natural framework for the analysis, but they do not provide a biological status for the detected segments. We propose a new model for this segmentation/clustering… CONTINUE READING
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