A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus.

@article{Jackson1992AST,
  title={A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus.},
  author={Ian J Jackson and Dwight McCoy Chambers and Kentaro Tsukamoto and Neal G. Copeland and Debra J. Gilbert and Nancy A. Jenkins and Vincent J. Hearing},
  journal={The EMBO journal},
  year={1992},
  volume={11 2},
  pages={527-35}
}
We have cloned and sequenced mouse cDNAs corresponding to a third member of a family of melanocyte-specific mRNAs, which encode tyrosinase and related proteins. This new member, tyrosinase-related protein-2 (TRP-2), has approximately 40% amino acid identity with the two other proteins in the family and has the same structural features including two copper binding sites, two cysteine-rich regions, a signal peptide and a transmembrane domain. We now show that one of the cysteine-rich regions in… CONTINUE READING
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