A second immunoglobulin light chain isotype in the rainbow trout

@article{Partula1996ASI,
  title={A second immunoglobulin light chain isotype in the rainbow trout},
  author={Sylvie Partula and Joseph Schwager and Sirje Timmusk and Lars Pilstr{\"o}m and Jacques Charlemagne},
  journal={Immunogenetics},
  year={1996},
  volume={45},
  pages={44-51}
}
 A novel immunoglobulin (Ig) light chain isotype, termed IgL2, has been isolated from trout lymphoid tissues both by reverse transcription – polymerase chain reaction (PCR) and screening of cDNA libraries. The CL domain of the new isotype shares only 29% residues with a recently cloned trout IgL isotype, termed IgL1, which has some similarities to Cκ and Cλ isotype domains of several vertebrate species. Using anchored PCR, a VL element rearranged to CL2 was isolated. It is a member of a new VL… CONTINUE READING

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