A scaffold-free in vitro model for osteogenesis of human mesenchymal stem cells.

@article{Hildebrandt2011ASI,
  title={A scaffold-free in vitro model for osteogenesis of human mesenchymal stem cells.},
  author={Cornelia Hildebrandt and Heiko B{\"u}th and Hagen Thielecke},
  journal={Tissue & cell},
  year={2011},
  volume={43 2},
  pages={
          91-100
        }
}
For studying cellular processes three-dimensional (3D) in vitro models are of a high importance. For tissue engineering approaches osseous differentiation is performed on 3D scaffolds, but material depending influences promote cellular processes like adhesion, proliferation and differentiation. To investigate developmental processes of mesenchymal stem cells without cell-substrate interactions, self-contained in vitro models mimicking physiological condition are required. However, with respect… CONTINUE READING

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