A rule-based model of insulin signalling pathway

Abstract

The insulin signalling pathway (ISP) is an important biochemical pathway, which regulates some fundamental biological functions such as glucose and lipid metabolism, protein synthesis, cell proliferation, cell differentiation and apoptosis. In the last years, different mathematical models based on ordinary differential equations have been proposed in the… (More)
DOI: 10.1186/s12918-016-0281-4

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