A role of polycomb group genes in the regulation of gap gene expression in Drosophila.

@article{Pelegri1994ARO,
  title={A role of polycomb group genes in the regulation of gap gene expression in Drosophila.},
  author={F Pelegri and Ruth Lehmann},
  journal={Genetics},
  year={1994},
  volume={136 4},
  pages={1341-53}
}
Anteroposterior polarity of the Drosophila embryo is initiated by the localized activities of the maternal genes, bicoid and nanos, which establish a gradient of the hunchback (hb) morphogen. nanos determines the distribution of the maternal Hb protein by regulating its translation. To identify further components of this pathway we isolated suppressors of nanos. In the absence of nanos high levels of Hb protein repress the abdomen-specific genes knirps and giant. In suppressor-of-nanos mutants… CONTINUE READING

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