A role of mast cell glycosaminoglycans for the immunological expulsion of intestinal nematode, Strongyloides venezuelensis.

@article{Maruyama2000ARO,
  title={A role of mast cell glycosaminoglycans for the immunological expulsion of intestinal nematode, Strongyloides venezuelensis.},
  author={Haruhiko Maruyama and Yoshisada Yabu and Atsushi Yoshida and Yukifumi Nawa and Nobuo Ohta},
  journal={Journal of immunology},
  year={2000},
  volume={164 7},
  pages={3749-54}
}
We examined effects of mast cell glycosaminoglycans on the establishment of the intestinal nematode, Strongyloides venezuelensis, in the mouse small intestine. When intestinal mastocytosis occurred, surgically implanted adult worms could not invade and establish in the intestinal mucosa. In mast cell-deficient W/Wv mice, inhibition of adult worm invasion was not evident as compared with littermate +/+ control mice. Mucosal mastocytosis and inhibition of S. venezuelensis adult worm mucosal… CONTINUE READING

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