A role for the interferon-inducible protein 10 in inhibition of angiogenesis by interleukin-12.

@article{Angiolillo1996ARF,
  title={A role for the interferon-inducible protein 10 in inhibition of angiogenesis by interleukin-12.},
  author={Anne L. Angiolillo and Cecilia Sgadari and Giovanna Tosato},
  journal={Annals of the New York Academy of Sciences},
  year={1996},
  volume={795},
  pages={
          158-67
        }
}
We have developed a nude mouse model in which tumor regression is reproducibly induced by coinjection with or intratumor inoculation of EBV-immortalized B cells. A wide spectrum of tumor-derived human cell lines can be established as subcutaneous tumors in sublethally irradiated athymic mice. Most of these tumors are induced to regress by human B cells immortalized with EBV. The tumor regression process is characterized by superficial necrosis and scarring that progressively extends itself to… CONTINUE READING
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