A role for the fibroblast growth factor receptor in cell fate decisions in the developing vertebrate retina.

@article{McFarlane1998ARF,
  title={A role for the fibroblast growth factor receptor in cell fate decisions in the developing vertebrate retina.},
  author={Sarah McFarlane and Michael E Zuber and Christine E Holt},
  journal={Development},
  year={1998},
  volume={125 20},
  pages={
          3967-75
        }
}
The mature vertebrate retina contains seven major cell types that develop from an apparently homogenous population of precursor cells. Clonal analyses have suggested that environmental influences play a major role in specifying retinal cell identity. Fibroblast growth factor-2 is present in the developing retina and regulates the survival, proliferation and differentiation of developing retinal cells in culture. Here we have tested whether fibroblast growth factor receptor signaling biases… CONTINUE READING

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