A role for the extracellular domain of Crumbs in morphogenesis of Drosophila photoreceptor cells.

@article{Richard2009ARF,
  title={A role for the extracellular domain of Crumbs in morphogenesis of Drosophila photoreceptor cells.},
  author={M{\'e}lisande Richard and Nadine Muschalik and Ferdi Grawe and Susann Oz{\"u}yaman and Elisabeth Knust},
  journal={European journal of cell biology},
  year={2009},
  volume={88 12},
  pages={765-77}
}
Morphogenesis of Drosophila photoreceptor cells includes the subdivision of the apical membrane into the photosensitive rhabdomere and the associated stalk membrane, as well as a considerable elongation of the cell. Drosophila Crumbs (Crb), an evolutionarily conserved transmembrane protein, organizes an apical protein scaffold, which is required for elongation of the photoreceptor cell and extension of the stalk membrane. To further elucidate the role played by different Crb domains during eye… CONTINUE READING
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