A role for the aryl hydrocarbon receptor in cardiac physiology and function as demonstrated by AhR knockout mice

@article{Vsquez2003ARF,
  title={A role for the aryl hydrocarbon receptor in cardiac physiology and function as demonstrated by AhR knockout mice},
  author={Alejandro V{\'a}squez and Nader H Atallah-Yunes and F. C. Smith and Xiaomang You and Sharon E. Chase and Allen E. Silverstone and Karen L. Vikstrom},
  journal={Cardiovascular Toxicology},
  year={2003},
  volume={3},
  pages={153-163}
}
The aryl hydrocarbon receptor (AhR), a ligand activated transcription factor, is the receptor for the polycyclic aromatic hydrocarbons found in tobacco smoke, polychlorinated biphenyls, and the environmental pollutant, dioxin. To better understand the role of the AhR in the heart, echocardiography, invasive measurements of aortic and left ventricular pressures, isolated working heart preparations, as well as morphological and molecular analysis were used to investigate the impact of AhR… CONTINUE READING

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