A role for the NG2 proteoglycan in glioma progression.

@article{Stallcup2008ARF,
  title={A role for the NG2 proteoglycan in glioma progression.},
  author={William B Stallcup and Feng-Ju Huang},
  journal={Cell adhesion & migration},
  year={2008},
  volume={2 3},
  pages={192-201}
}
Many human gliomas carry markers characteristic of oligodendrocyte progenitor cells (such as Olig-2, PDGF alpha receptor and NG2 proteoglycan), suggesting these progenitors as the cells of origin for glioma initiation. This review considers the potential roles of the NG2 proteoglycan in glioma progression. NG2 is expressed not only by glioma cells and by oligodendrocyte progenitors, but also by pericytes associated with the tumor microvasculature. The proteoglycan may therefore promote tumor… CONTINUE READING

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