A role for receptor tyrosine phosphataseζ in glioma cell migration
@article{Mueller2003ARF, title={A role for receptor tyrosine phosphataseζ in glioma cell migration}, author={S. Mueller and P. Kunkel and K. Lamszus and U. Ulbricht and G. A. Lorente and A. Nelson and D. V. Schack and Daniel J Chin and S. Lohr and M. Westphal and T. Melcher}, journal={Oncogene}, year={2003}, volume={22}, pages={6661-6668} }
Glioblastomas (GBM) are the most frequent and malignant human brain tumor type. Typically striking in adulthood, tumor progression is rapid, relentless, and ultimately leads to the patient's death within a year of diagnosis. The identification of transcriptionally regulated genes can lead to the discovery of targets for antibody or small-molecule-mediated therapy, as well as diagnostic markers. We prepared cDNA arrays that are specifically enriched for genes expressed in human brain tumors and… CONTINUE READING
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References
SHOWING 1-10 OF 33 REFERENCES
Expression of a Cleaved Brain-Specific Extracellular Matrix Protein Mediates Glioma Cell Invasion In Vivo
- Biology, Medicine
- The Journal of Neuroscience
- 1998
- 110
- PDF
Glial tumor cell adhesion is mediated by binding of the FNIII domain of receptor protein tyrosine phosphatase β (RPTPβ) to tenascin C
- Biology
- Oncogene
- 2001
- 38
- PDF
cDNA expression array reveals heterogeneous gene expression profiles in three glioblastoma cell lines
- Biology, Medicine
- Oncogene
- 1999
- 62
- PDF
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2001
- 221
- PDF
"...those left behind." Biology and oncology of invasive glioma cells.
- Biology, Medicine
- Neoplasia
- 1999
- 159
Soluble forms of NCAM and F3 neuronal cell adhesion molecules promote Schwann cell migration: identification of protein tyrosine phosphatases ζ/β as the putative F3 receptors on Schwann cells
- Biology, Medicine
- Journal of neurochemistry
- 2001
- 47
Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1996
- 3,039
- PDF