A role for prefrontal cortex in the extinction of a conditioned taste aversion.

@article{Mickley2005ARF,
  title={A role for prefrontal cortex in the extinction of a conditioned taste aversion.},
  author={G. Andrew Mickley and Cynthia L Kenmuir and Anna M Yocom and Justin A. Wellman and Jaclyn M Biada},
  journal={Brain research},
  year={2005},
  volume={1051 1-2},
  pages={176-82}
}
This study used immunohistochemical methods to determine if the medial prefrontal cortex (mPFC) is involved in the extinction of a conditioned taste aversion (CTA). As rats reached 90% reacceptance of a tastant (saccharin: SAC) that had previously been associated with lithium chloride-induced malaise, c-Fos protein expression increased dramatically as compared to animals with active CTAs, animals without CTAs (i.e., explicitly unpaired CS-US exposures) or animals drinking SAC for the first time… CONTINUE READING
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