A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast.

@article{Sreenivas1998ARF,
  title={A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast.},
  author={Avula Sreenivas and Jana Patton-Vogt and Valeria Bruno and Peter Griac and Susan A Henry},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 27},
  pages={16635-8}
}
The SEC14 gene encodes a phosphatidylinositol/phosphatidylcholine transfer protein essential for secretion and growth in yeast (1). Mutations (cki1, cct1, and cpt1) in the CDP-choline pathway for phosphatidylcholine synthesis suppress the sec14 growth defect (2), permitting sec14(ts) cki1, sec14(ts) cct1, and sec14(ts) cpt1 strains to grow at the sec14(ts… CONTINUE READING