A role for noradrenaline in pre-eclampsia: towards a unifying hypothesis for the pathophysiology.

@article{Manyonda1998ARF,
  title={A role for noradrenaline in pre-eclampsia: towards a unifying hypothesis for the pathophysiology.},
  author={Isaac T. Manyonda and D. M. Slater and Christiane Fenske and David Hole and Mei Yee Choy and Caroline Wilson},
  journal={British journal of obstetrics and gynaecology},
  year={1998},
  volume={105 6},
  pages={641-8}
}
OBJECTIVE To compare plasma catecholamine (noradrenaline and adrenaline) levels in pre-eclamptic to normotensive pregnancy, and to study the activity of synthetic enzymes for catecholamines in placental and trophoblastic cell cultures. We postulated that catecholamines might be an important signal secreted by the fetoplacental unit in pre-eclampsia. METHODS We recruited 12 women with pre-eclampsia and 12 pregnant women with nonproteinuric hypertension undergoing delivery by caesarean section… CONTINUE READING
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